Multi-System Mutation Design for Substrate Selectivity
Graphical abstract
Summary
Multiple anonymized protein–substrate systems are docked and locally scanned to compare mutation effects and create region-level experimental priorities. The graphical abstract brings together the principal sequence, structure and property results across candidates. The combined evidence establishes actionable priorities for sequences, sites or peptide candidates. The result-focused presentation supports efficient review of the main evidence and research priorities.
Computational results
Structure-quality and homology-model review
Structure-quality and homology-model review. The original method schematic shows relative effect direction only, without sequences, residue numbers, substrate names or exact scores.
This figure presents the principal structures and trends in “Structure-quality and homology-model review” and connects them to the case-level ranking and result interpretation.
Full case PDF
Complete results, high-resolution figures and analysis are provided in the client PDF. Add our service account on WeChat and send HS-CASE-0025 to request it.